The Health Insurance Portability and Accountability Act (HIPAA) of 1996 introduced a sweeping set of regulations that have had a broad-reaching impact across all areas of the health care industry. Achieving compliance with these regulations, while at the same time minimizing any disruptions to normal business operations, has become a careful balancing act for many enterprise organizations in the health care sector. This paper will illustrate how Red Hat Enterprise Virtualization for Desktops can help these organizations comply with specific HIPAA mandates, while at the same time increasing their overall efficiency and agility.